January 2018: New NOREPOS research project

The NOREPOS research network has received a grant from the Research Council of Norway (FRIMEDBIO) to carry out a large research project in the period 2018-2021. FRIMEDBIO funds independent research projects within medicine, health sciences and biology. In particular, the FRIMEDBIO scheme aims to promote “scientific quality at the forefront of international research” and “boldness in scientific thinking and innovation”. Our new research project is entitled: Novel aspects of an old problem. The Norwegian Epidemiologic Osteoporosis Studies. The project has three work packages affiliated at the Norwegian Institute of Public Health, the University of Bergen, and the University of Oslo, respectively. Two Post Doc positions and one Researcher position will be announced during spring 2018. More information about the project is available here.

September 2015: Anniversary paper about NOREPOS is published

On the occasion of the 10th Annual NOREPOS Workshop this year, a paper describing the history of epidemiologic osteoporosis research in Norway is published in the Norwegian Journal of Epidemiology. The topic of the current issue is the History of Epidemiology in Norway. The paper written by Anne Johanne Søgaard and Grethe S Tell is entitled: An example of a successful national research network in epidemiology – The Norwegian Epidemiologic Osteoporosis Studies (NOREPOS).

April 2015: Date and venue set for the 10th Annual NOREPOS Workshop

The 10th Annual NOREPOS Workshop will take place in Scandic Hotel Nidelven, Trondheim, 27 – 28 October 2015. The program will be announced here.

April 2015: Seminar about geodata and fracture at the Norwegian Institute of Public Health

The Norwegian Institute of Public Health carried out an open seminar with the topic “Kan geodata knekke bruddgåten?”

View programme (in Norwegian).

October 2014: NOREPOS cohort profile published

The background paper describing the NOREPOS network and data material is now available online. Reference:

Søgaard AJ, Meyer HE, Emaus N, Grimnes G, Gjesdal CG, Forsmo S, Schei B, Tell GS. Cohort profile: Norwegian Epidemiologic Osteoporosis Studies (NOREPOS). Scand J Public Health 2014 Oct 2 [Epub ahead of print]

View full publication online at SAGE journals

September 2014: Dissertation: Vitamin K, inflammation, and osteoporosis

On 23 September, rheumatologist Ellen M Apalset defended her thesis “Vitamin K and inflammation in relation to bone mineral density and hip fractures” at the University of Bergen.

The study is based on data from the Hordaland Health Study (HUSK), which was conducted from 1997 to 1999 with 10 years follow-up of hip fractures recorded by the hospitals in the county.

Dietary vitamin K1 and K2 and blood markers of interferon-gamma mediated inflammation were examined.

Low dietary vitamin K1 diet was associated with low bone density among women but not in men. Older people (71-74 years) with a low intake of vitamin K1 had an increased risk of hip fracture. Vitamin K2 in the diet showed no association with bone density or risk of hip fracture.

Among the oldest there was an association between higher blood levels of certain inflammation markers and low bone density. In middle-aged people (47-49 years) there was no such correlation. The oldest also had a greater risk of hip fracture at higher levels of inflammation markers.

High intake of vitamin K1 is related to a healthy diet and lifestyle, and the study cannot conclude as to whether vitamin K1 protects against osteoporosis and fractures. A link between inflammation and osteoporosis has been shown also earlier, but this is the first time this part of the immune system has been studied in the context of bone density and fracture risk in a larger population study.

Read more (in Norwegian)

June 2014: New NOREPOS Dissertation

Cecilie Dahl defended her thesis 2 June 2014, entitled: “Quality of municipal drinking water and the risk of osteoporotic fractures in Norway”.

The dissertation consists of three sub-studies where Dahl studied differences in fracture risk according to drinking water quality in nationwide data. Results from the first sub-study showed that the drinking water that was slightly acidic often was less hygienic, and it was also associated with a higher incidence of forearm fractures. In the second sub-study, Dahl found that a higher magnesium content in drinking water could be protective against hip fracture, whereas a higher level of calcium was not associated with hip fractures.

In the third sub-study, the concentrations of metals such as lead, cadmium and aluminum in drinking water were examined. A higher level of the heavy metal cadmium was associated with increased risk of hip fractures in men. More lead in drinking water also appeared to be associated with increased risk of hip fractures in both genders, but a statistical association was only seen in the oldest (66-85 years).

The results show that the quality of drinking water, in particular low magnesium content, is correlated with high incidence of osteoporotic fractures in Norway. Since this is the first study of its kind in the world, we need more studies before concluding. The next step will be to examine how substances in drinking water may affect bone health.

March 2014: Date and venue set for NOREPOS workshop 2014

The 9th annual NOREPOS workshop will take place 18-19 June in Solstrand Hotel & Bad outside Bergen. The final program will be announced in May. More information

November 2013: Dissertation: Svanhild Waterloo

Cand. san. Svanhild Haugnes Waterloo will defend her thesis for the degree Ph.D. in the University of Tromsø Friday 8th November 2013. The topic is vertebral fractures in the sixth Tromsø study.

May 2013: Date and venue set for next NOREPOS workshop

This year’s NOREPOS workshop will take place 26-27 August in beautiful Malangen Brygger in Troms, approximately one hour drive from Langnes Airport in Tromsø. The program will be announced here.

NIPH website: “Risikoen for hoftebrudd faller, men fortsatt rundt 9000 brudd per år”

Read here

February 2012: Date and venue set for this year’s NOREPOS workshop

This year’s NOREPOS workshop will take place 20-21 September in Hurdalsjøen in Akershus, 30 minutes drive north of Gardermoen Airport. Please mark the dates in your calendar now! More information will be available soon.

February 2012: Norwegian data in FRAX®

We have contributed our nationwide data on hip fracture incidence to the World Health Organization’s Fracture Risk Assessment Tool. The calculation tool to estimate individual ten-year risk of fracture based on common risk factors is now adapted to Norwegian conditions. It can be found here.

Acknowledgements: Tone K. Omsland and Haakon E. Meyer on behalf of the NOREPOS collaboration

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